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Therefore, increased bilirubin levels caused by abnormal processing by the liver and/or blocked excretion disrupt the balance between the production and elimination of bilirubin, which may be key factors causing neonatal hyperbilirubinemia (21)

The Journal of Biological Chemistry , 279 , 2244922460

Besides, protein undergoes carbonylation, another form of protein oxidative modification in which ROS groups bind to specific amino acids, affecting protein stability and activity ( Furthermore, ROS/RNS can directly attack DNA, causing oxidative DNA damage in IBD ( 2.3 Mitochondrial dysfunction Mitochondria, with their functions in energy production, calcium homeostasis, and membrane excitability, are thought to substantially impact the pathology of IBD, as their dysfunction may initiate and advance the disease

Hormone Therapy When hormone levels become out of balance, it can produce a wide range of symptoms and health issues

A study indicating the deleterious impact of HIV and SIV on fat fibrosis