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Intraventricular injection of CNTF in EAE mice reduced expression of inflammatory cytokines TNF- and interferon- and decreased demyelination and neurodegeneration (117)

In MS, clinical therapies aimed to block TNF--mediated pro-inflammatory effects (Van Oosten et al., 1996

The exogenous addition of ascorbic acid to tobacco cells during cell division reduced the intracellular MDA content and also accelerated the rate of cell division, which contributed to the reduction of cell membrane permeability and soluble protein content as well as the stability of cell membrane structure 26