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Statements Author contributions MC: Conceptualization, Writing original draft, Writing review & editing

Ann Gastroenterol Surg 4:2129 Liu A, Arbiser JL, Holmgren A, Klein G, Klein E (2005) PSK and Trx80 inhibit B-cell growth in EBV-infected cord blood mononuclear cells through T cells activated by the monocyte products IL-15 and IL-12

In synergy with IL-36Ra, IL-36 promotes the intestinal inflammation through the NF-KB pathway, which maintains the homeostasis by balancing the pro- and anti-inflammatory responses in the TME (88)

2017;8:e2970

Adeva-Andany MM, Prez-Felpete N, Fernndez-Fernndez C, Donapetry-Garca C, Pazos-Garca C

Diagnosis relies on B12 levels, methylmalonic acid, homocysteine, and intrinsic-factor antibodies interpreted by a clinician