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Defects occur in both the NADPH oxidase complex itself and the enzymes of the PPP that yield the required NADPH, particularly G6PDH The Pentose Phosphate Pathway The pentose phosphate pathway (PPP) (also called hexose monophosphate shunt, HMS) consists of series of interconnected reactions that serve as an alternate route for the metabolism of glucose

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doi: 10.1016/S0306-9877(98)90270-5 110 RossignolDAFryeRE

The changing epidemiology of invasive fungal infections