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Heydarpour F, Hemati N, Hadi A, Moradi S, Mohammadi E, Farzaei MH

10.1136/bcr-2021-245040 Sean R Smith, Mary Vargo, David S Zucker, Maryanne Henderson, Samman Shahpar, Eric M Wisotzky, Christian Custodio, Jeffrey Basford, Gina Jay, Lynn Gerber, Andrea Cheville

Notably, a review by Sies highlights superoxide (O 2 ) and hydrogen peroxide (H 2 O 2 ) as secondary messengers in various signaling pathways 10 , though H 2 O 2 is considered more important owing to its higher stability and diffusive nature

In contrast to most other zf-UBP domains, the USP20 and USP33 zf-UBP domains do not bind the ubiquitin C-terminus with measurable affinity (Supplementary Fig

EF can also play a role in pigment regulation, although individual components within Epimedium species can exert different effects on melanin function