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POR may promote lipid peroxidation by accelerating the cycling between Fe 2+ and Fe 3+ in heme [47]

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Therefore, reduced antioxidant capacity appears to be a consequence of disease progression and tissue damage rather than an initiating factor present throughout the entire disease course

AACR Special Conference on Chromatin and Epigenetics in Cancer

Personalized medicine, by considering genetic variations affecting antioxidant enzyme function or stress response pathways, could enhance oxidative stress therapies and potentially improve treatment outcomes

Studies conducted in Korea and Japan have also indicated that increased mushroom intake may reduce the incidence of gastric cancers [23-24]