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doi: 10.2215/CJN.08580718 130 SalibaA.DebnathS.TamayoI.TumovaJ.MaddoxM.SinghP.et al

Experimental validation Dose response curves and determination of IC 50 values were assessed for the 12 candidate drugs using 3-fold dilution series (see Supplementary Methods (Supplementary File 1) for more details)

For translational applications, sustained intranasal delivery aligns far closer with canonical, long-term longevity phenotypes Source: Open Access Paper: Middle-aged mice treated with GHK-Cu peptide administered intraperitoneally or intranasally show behavioral rescue but divergent hippocampal aging programs Institution: University of Washington, Seattle, WA Country: USA Journal: bioRxiv (Preprint) Impact Evaluation: The impact score of this journal is 0 (as a preprint server without a formal Clarivate index)

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In case if one expects a radical change similar to surgical facelift, HIFU therapy will hardly help