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HeA-enriched HEM extract was reported to reduce A plaques and gliosis in the cortex and hippocampus of 5-month-old female APPswe/PS1dE9 transgenic mice and increase NGF and hippocampal neurogenesis 20

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Furthermore, to estimate the effect of PR8 virus infection on glutaminolysis in which glutamine is converted to 2-ketoglutaric acid via glutamic acid and enters the TCA cycle, we compared the ratio of the peak areas of glutamic acid to those of glutamine and the ratio of the peak areas of ketoglutaric acid to those of glutamic acid

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