Based on these information we investigated whether heme and the different Hb redox forms induce NLRP3 inflammasome activation in ECs (Figure 3)
While glutathione is generally well-tolerated, understanding potential side effects is crucial to ensure safe use
ORCID: Affiliation: 11 Department of Neuroscience and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, 20149 Milano, Italy 12 Department of Pathophysiology and Transplantation, Dino Ferrari Center, Universit degli Studi di Milano, 20122 Milano, Italy These authors contributed equally to this work
This could introduce challenges for patients with lifelong anticoagulation needs, such as those with heart failure and atrial fibrillation (Yasueda et al., 2016) and could interact with antihypertensive drugs to cause an excessive drop in blood pressure, necessitating careful monitoring and dose adjustments (Zhao et al., 2022)
Cruelty-free and vegan
Elevated morphine concentrations in neonates treated with morphine and prolonged hypothermia for hypoxic ischemic encephalopathy