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Disclosures: Keiko Iwaisako: Nothing to Disclose, Momoko Fujita: Nothing to Disclose, Kaito Suzumura: Nothing to Disclose, Shuhei kanda: Nothing to Disclose, Daisuke Kyuno: Nothing to Disclose, Hiroto Nishino: Nothing to Disclose 1307 EFFECTIVENESS AND SAFETY OF TENOFOVIR ALAFENAMIDE FOR HBV PROPHYLAXIS IN HBV NEGATIVE RECIPIENTS OF ORTHOTOPIC LIVER TRANSPLANT WITH HBCAB+ DONORS:24 WEEKS INTERIM ANALYSIS Aiwei Zhou 1 Zhifeng Xi 2 Kang He 2 Hualian Hang 2 Hanyong Sun 2 Yongbing Qian 2 Wei Geng 2 Jie Cao 2 Lei Xia 2 Jianjun Zhang 2 Qiang Xia 2 , 1 Shanghai Jiaotong University School of Medicine, 2 Renji hospital Background: Liver transplantation (LT) is now the established standard of care for individuals suffering from end-stage liver disease

This was followed by a 1 ns equilibration under NVT conditions with positional force restraints of 1000 kJmol 1 nm 1 on C atoms, using a 20 fs timestep

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The resulting tiredness persists despite adequate rest and does not respond to early bedtimes or caffeine