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W.FleckensteinJ.GrafeP

Diabetes Care 2011, 34 (8), 18091815

When cells are overloaded with iron, excess Fe 2+ promotes the accumulation of lipid peroxidation and ROS through either enzymatic or non-enzymatic reactions (the Fenton reaction)

There is little high-quality long-term safety surveillance of the sort that would usually be expected before confidently promoting a peptide for preventive use in generally healthy people