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3.3 Mitochondrial dysfunction Mitochondrial dysfunction has been demonstrated to be a key pathogenic mechanism in multiple neurodegenerative diseases, including PD (Figure 3C) ( At slightly elevated unbound concentrations, BR exhibits toxicity toward astrocytes and neurons, leading to damage of mitochondria and plasma membranes

10.1002/anie.201904131 112 HuangH

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Vitamin D and intermittent fasting exert significant hepatoprotective effects in MASLD by improving metabolic parameters, enhancing antioxidant capacity, and attenuating inflammatory signaling

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Consistent daily timing at the same time each morning helps maintain stable blood levels and optimize results