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c) Phosphate buffer solutions (0.05M) in the pH range 6.0-8.0 were prepared by adding varying amount of dilute sodium hydroxide (0.1 M) to separate aliquots (50ml) of potassium dihydrogen phosphate (0.1M) and diluted with distilled water to 100ml

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Cytochrome c is released from the mitochondrial permeability transition pore (MPTP) due to damage or stress in mitochondria (138)

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The samples were pooled into libraries and sequenced on the Illumina NovaSeq 6000 at a minimum depth of 20,000 reads per cell

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer