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Suprachiasmatic nucleus: cell autonomy and network properties

Glossary Autophagy An evolutionarily conserved homeostatic process through which old, dysfunctional or potentially hazardous cytoplasmic components undergo lysosomal degradation

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Subsequently, vitamin D3 undergoes hydroxylation within the liver, resulting in calcidiole (25(OH)D3)

TLR4 activation has been directly implicated in PD pathogenesis, as demonstrated by elevated TLR4 expression in both human patients and murine models with PD, driving microglial activation and dopaminergic neuron loss (51)