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Wang W, Kryczek I, Dostl L, Lin H, Tan L, Zhao L, Lu F, Wei S, Maj T, Peng D, He G, Vatan L, Szeliga W, Kuick R, Kotarski J, Tarkowski R, Dou Y, Rattan R, Munkarah A, Liu JR, Zou W

The authors found that adding IGFBP-4 helped retain IGF-1 in the postoperative tendon, boosting protein synthesis through the IGF-1/AKT signaling pathway and effectively promoting tendon healing

However, at later stages, activated astrocyte proliferation can inhibit the plasticity and regeneration of the central nervous system [5, 6]

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