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In a 12-week study, participants experienced up to a 51.93% reduction in the Melasma Area and Severity Index (MASI) score

Sharov VS, Dremina ES, Galeva NA et al (2006) Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLCelectrospray-tandem MS: selective protein oxidation during biological aging

Neurobiol Aging 23: 737745, 2002

Identification of key genes modules linking diabetic retinopathy and circadian rhythm

While these functional improvements occurred in animal models, they suggest possible benefits for mobility and quality of life that would need confirmation in human trials