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doi: 10.1002/cph4.70042

Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation

Science 288 , 23792381 (2000)

As the wild-type HpTpx did not co-crystallize, we incubated the HpTpx C94A mutant (HpTpx_C R A) with Metro and Metro-P3 during protein expression, which resulted in co-crystal structures of 1.75 (PDB ID: 9F64) and 1.95 resolution (PDB ID: 9F65), respectively (Fig