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This results in the formation of an oxyanion intermediate before forming 5-oxoproline

Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis

Kopp MC, Larburu N, Durairaj V, Adams CJ, Ali MMU

doi: 10.1172/jci34060

Antioxidant supplements hold significant potential in mitigating ROS-mediated cellular and tissue damage, either by directly neutralizing free radicals, as seen with vitamins C and E, or by supporting enzymatic defense systems such as superoxide dismutase and catalase, which actively scavenge free radicals (Poljsak et al., 2013