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Dataset 2: = 0.081, 95% CI: 0.0250.136, p = 0.004) (He et al., 2022)

Similarly, MMP-7, which is highly expressed in IPF lung tissue and plasma, is secreted by damaged AECs and drives fibrosis through multiple mechanisms, including cleaving basement membrane components such as E-cadherin and integrin 4, activating bioactive molecules including osteopontin and TGF-, and promoting fibroblast activation and collagen deposition (Richards et al., 2012)

Vitamin A, a powerful antioxidant, fights off harmful things that can age your skin and helps keep collagen strong

GSH activates glutathione peroxidase 4 (GPX4) to maintain the balance of the antioxidant system [10, 11]

10.1371/journal.pone.0099598 208

Updated 8/28/2023