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Dual inhibition of the MEK-ERK pathway (classical tumor signaling pathway) and Gln metabolism can induce redox stress, as evidenced by reduced mitochondrial membrane potential, elevated ROS levels, and inhibition of Gln degradation, and may be an effective therapeutic strategy for KRAS -driven NSCLC ( KRAS -driven cancer cells bypass the Gln-dependent G1 cell cycle checkpoint and are arrested in s-phase when Gln utilization is inhibited

Weller M, Le Rhun E

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Figure 12(b, c) show the antibacterial effect of rGO-WiOC and rGO-WiC against two Gram-positive bacteria (Streptococus pyogenes and Staphylococus aureus) and two Gram-negative bacteria (Escherichia coli and Klebsiella pneumonia), quantified by the area of the zone formed around the disc