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Create a cool, dark, and quiet sleep environment to support melatonin production

Collectively, these results suggest that the knockout of neuronal Slc25a39 negates the protective effects of FGF21 against oxidative stress and apoptosis following TBI in mice

High levels of oxidative stress may lead to infertility issues

Concurrently, ferroptosis-mediated tubular and endothelial cell damage reduces renal microvascular density (capillary rarefaction) and impairs oxygen delivery, establishing a hypoxic microenvironment

, Therefore, we used an RNAscope probe against Slc7a11 and revealed its expression within TLS (Figure 3B)

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