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Contraindications: Renal failure, G6PD deficiency, uncontrolled hypertension

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orcid.org/0000-0002-9905-9138 This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In animal models, exposure to lead acetate led to inhibition of ALAS in blood, activation of plasma CAT, elevation of MDA and GSSG, reduction in the level of plasma GSH, and an increase in oxygen free radicals ( Figure 1 ) [64]