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Without coenzyme B12, tetrahydrofolate cannot be produced from 5-methyl tetrahydrofolate leading to folate deficiency

MRS data acquisition and analysis Spectra were obtained on a 3T GE Discovery MR750 (SW: DV26 R01) scanner from two regions of interest: anterior cingulate cortex (ACC) and left dorsolateral prefrontal cortex (DLPFC) (Figure 1)

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