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Reported preclinical effects on sleep architecture and stress endpoints are not of a magnitude that would predict robust clinical signal even if a clean delivery system were available

Loomba, R., Bettencourt, R

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Increase of circulating Cxcl9 and Cxcl11 associated with euthyroid or subclinically hypothyroid autoimmune thyroiditis

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Sharina and Martin, 2017) (Figure 1)