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J Acad Nutr Diet 2015;115:50-63

This binding initiates an intracellular signaling cascade, promoting gene expression related to cell survival, proliferation, and migration, ultimately leading to the formation of new capillary networks and enhanced tissue perfusion

Fazakerley, D

Additionally, copper ions in GHK-Cu can catalyze oxidation of certain peptides (such as those containing cysteine residues), leading to cross-reactivity and degradation