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Then, the resulting data matrixes were imported into SIMCA 14.0 software (Umetrics, Sweden) for multivariate data analysis, including principal component analysis (PCA) and orthogonal partial least square discriminant analysis (OPLS-DA)

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10.3390/ijms24010415 122 SpencerE.RosengraveP.WillimanJ.ShawG.CarrA

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The researchers conclude: Our findings, together with those of previous studies (7, 8, 19, 20), suggest that the current RDA of 2.4 mcg vitamin B-12/d may be inadequate for optimal biomarker status

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