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doi: 10.1007/s11103-015-0348-4 146 LandschulzW

many of the same cytokines can trigger production of ROS from the mitochondria and other oxidative organelles in cells, a self-perpetuating cycle

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The negative results of the clinical trials with antioxidants prompted new studies focusing on the mechanisms of oxidative stress in diabetes in order to develop causal antioxidant therapy