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doi: 10.1016/j.drup.2017.05.002 169 LeiHPeiZJiangCChengL

While the treatment for pruritus stemming from cholestatic liver disorders is established, pruritus originating from non-cholestatic causes is frequently encountered in cirrhotic patients due to various non-cholestatic factors

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In controlled laboratory research environments, it is extensively studied for its involvement in cellular growth pathways, protein synthesis regulation, and peptide-mediated signaling networks

"We were able to confirm their functions and then look at bigger picture trends, like the relationship of that gene to different kinds of diseases," said Keith Dufault-Thompson, Ph.D., a staff scientist in NLM's Division of Intramural Research (DIR)