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Such fine modulation of movement across the epithelium demands structural components that aid this process, such as transmembrane proteins including occludin, junctional adhesion molecules, and claudin protein family members that together maintain epithelial cell basolateral polarity (Shin et al

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Inflammation also involves in many cardiovascular diseases, although whether inflammation causes a heart attack or other cardiovascular disorders require further investigation, inflammation serves as a universal sign for the atherogenic response