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Indeed, during APAP-induced toxicity there is an increased generation of mitochondrial superoxide anion production, stimulated by impaired mitochondrial respiration and formation of adducts between the reactive metabolite NAPQI and sulfhydryls moieties from mitochondrial proteins (Yan et al., 2010)

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Effects of rumen-protected methionine and choline supplementation on the steroidogenic potential of the first postpartum dominant follicle and expression of immune mediators in Holstein cows

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The FDA approved a label change to add the following ophthalmologic findings to subsection 5.1 (Warnings and Precautions

A 5-fold increase of hepatic lipid peroxidation, 9.5-fold increase of plasma 8-isoprostane level and increased expression of hepatic metallothionein were observed (136)