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Differential expression analysis was performed in R using the edgeR package (Robinson, McCarthy et al

doi: 10.1053/j.gastro.2013.11.049 53 EissingLSchererTTdterKKnippschildUGreveJWBuurmanWAet al

45,46 Increasingly, more studies have shown that G6PD activity is increased in several types of cancers, including bladder, breast, prostate, gastric cancers compared with normal tissues, and the high expression of G6PD predicts poor clinical outcome in various cancer patients and plays critical roles in tumorigenesis and chemoresistance

J Endotoxin Res 8:319327, doi:10.1177/09680519020080050501 Lu SC, Ge JL (1992) Loss of suppression of GSH synthesis at low cell density in primary cultures of rat hepatocytes

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