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The Metabolic Profile of Down Syndrome Down syndrome is a complex metabolic and genetic disorder whose root cause, trisomy 21, is an extra copy of chromosome 21 [59]

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The preclinical study, published in the Journal of Nanobiotechnology, was led by Associate Professor Chester Lee Drum, Department of Medicine and the Cardiovascular-Metabolic Disease Translational Research Programme (TRP), NUS Medicine, together with co-first authors Dr Muthu Kumaraswamy Shanmugam and Dr Girish Vallerinteavide Mavelli, both Senior Research Fellows at the Department of Medicine, NUS Medicine

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Endoplasmic reticulum stress is associated with autophagy and cardiomyocyte remodeling in experimental and human atrial fibrillation

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