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Ismail AM, et al

Krzemieniecki K, Sevelda P, Erdkamp F, Smakal M, Schwenkglenks M, Puertas J,

Propionyl-L-carnitine (200 mg/kg, p.o., drinking water) increases NO synthesis by enhancing eNOS expression in spontaneously hypertensive rats [8]

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In the author's observations, making treatment decisions contingent of the blood levels of co-enzyme Q10, carnitine and amitriptyline was very helpful in many cases, as children with sub-optimal clinical improvement always demonstrated a low level of at least one of the three agents, and increased dosing was associated with the resolution of episodes

Main clinical manifestations include chronic cough, sputum production, and wheezing, with primary pathological features encompassing inflammatory cell infiltration, excessive mucus secretion, and destruction of alveolar walls (Chen et al