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Based on the types of cancer and the anticancer drug mechanism, various combinations of enzyme-specific linkers and anticancer drugs constitute the diverse structure of prodrugs

doi: 10.1111/j.1749-6632.2009.04453.x 40 SaradhaBMathurPP

It is important to attribute these findings to IGF-1 biology broadly not to IGF-1 LR3 specifically, which was rarely the molecule tested in the landmark studies