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10.1186/1479-7364-3-3-281 173 Veterans Administration Cancer Chemotherapy Study Group, SimonK.ShirleyR.RichardW

How Resting Microglia and the M1/M2 Divide Are Being Rethought 2025-11-13 Microglia, the resident macrophages of the central nervous system (CNS), which are primarily established during development and account for approximately 5%-12% of the cells within the Central Nervous System (CNS)

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There is a downregulation of proteins involved in pericyte-endothelial cell communication [76,77,78] and astrocytes, being a glia cell, become activated

In stem cell models, it has been associated with increased integrin expression and markers of proliferative potential, raising interest in its role in regenerative contexts

PLoS ONE 11 , e0149122 (2016)