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ER primarily regulates nuclear gene transcription, while ER localizes to mitochondrial membranes, modulating mitochondrial metabolism and cellular stress responses (56)

All other semen parameters evaluated were unaffected

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High concentrations of ROS promote the activation of the ULK1 complex, a key substance in the initiation phase of autophagy, by promoting the AMPK signaling cascade and inhibiting the mTORC1 pathway, and are also able to promote BECN1