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The quantification of the total amounts of succinate and malate was performed employing a Bruker Advance UHPLC system coupled to ESI-MS/MS (EVOQTQMS) for chromatographic separation, fragmentation and quantification as described in Larsen ( Larsen, T.M

[DOI] [PubMed] [Google Scholar] 35.Brodersen H.P., Holtkamp W., Larbig D., Beckers B., Thiery J., Lautenschlager J., Probst H.J., Ropertz S., Yavari A

Potential insulin sensitivity changes While no direct evidence suggests a negative effect on blood sugar, some peptides may affect insulin signaling over time