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Overexpression of the PKC isoform increases the susceptibility of substantia nigra neurons, but PKC inhibitors such as chelerythrine decrease the -synuclein aggregation in dopaminergic cells caused by rotenone (Kabiraj et al., 2015)

For the objects in SeuratObject, the NormalizeData function of the Seurat package was used for normalization, FindVariableFeature was used for searching highly variable genes and ScaleData function was centralized (with the default parameter)

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