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Prednisone, like other corticosteroids should not be administered concomitantly with: - Barbiturates, carbamazepine, phenytoin, rifampin or ephedrine: these drugs enhance the metabolism of corticosteroids reducing their therapeutic action

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Glycemic control: In type 2 diabetes patients, HbA1c dropped by 1.32.0% (from ~8.0% to ~6.0%) with 412 mg doses [1]

High-intensity physical activity, typical of competitive or extreme sports, is correlated with a high incidence of gastrointestinal disorders and symptoms of increased intestinal permeability