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Here, we demonstrated that preferential accumulation of peroxidized phospholipids and loss of the antioxidant enzyme glutathione peroxidase 4 (GPX4) were responsible for vulnerability of midbrain dopaminergic neurons and progressive motor dysfunctions in a mouse model of PD

The author reported augmented deposition of collagen, oxidative stress, and phosphorylated p38 protein in DNP rats, which were reversed by melatonin ( Melatonin alone or in combination with drugs such as gabapentin enhanced the hepatic gene expression of peroxisome proliferatoractivated receptor and mitochondrial transcription factor-A

Ghevariya H, Singh R (2023) Functional foods and phytochemicals

Yoon DS, Park JC, Park HG, Lee JS, Han J

a saber, la determinacin de una concentracin tolerable obtenida dividiendo un nivel de efecto irritante en el tracto respiratorio de los roedores por un factor de incertidumbre, y la estimacin del riesgo de cncer mediante extrapolacin linear

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