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Neonatal purulent meningitis (NPM), a common central nervous system infection in neonates, exhibits elevated levels of cytokines IL-6 and IL-10 in cerebrospinal fluid, indicating their involvement in NPM pathogenesis [24-25]

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Due to the spatially close histidine-residue, the cysteine sulfhydryl group is particularly reactive and, in turn, can be readily regulated by oxidative or nitrosative stress [135] or become inactivated by alkylation reactions with reactive electrophiles, such as acrolein