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We describe an inverse relationship between MYC and GCLC, the ratelimiting enzyme of GSH biogenesis, in a mouse model of MYCdriven liver cancer

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3.4.3 Mechanistic insight Metformin mitigates DOX-induced cardiotoxicity through both AMPK-dependent and -independent mechanisms

Qiao L, Chen Y, Song X, Dou X, Xu C (2022) Selenium nanoparticles-enriched lactobacillus casei ATCC 393 prevents cognitive dysfunction in mice through modulating microbiota-gut-brain axis

Cells were transfected with 2 g of the indicated pCMV-HA-LMP1 plasmids together with 0.5 g of pRK5-Flag-TRAF6 plasmids or empty vector, 0.05 g of NF-B luciferase reporter 3xB-Luc and 0.2 g of pPGK-Renilla housekeeping control reporter using the PolyFect transfection reagent (Qiagen) 33

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