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By moderating this pathway, it may help reduce the low-grade inflammatory load associated with a range of ongoing conditions

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Bitian Liu, [email protected];[email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Distribution primarily involves the face including the periorbital region, muzzle, perioral area (commissures and lip margins), chin, and ears