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For example, key coinhibitory receptors such as PD-1, LAG-3, and TIGIT are coordinately upregulated in T cells through a shared transcriptional regulatory module involving c-Fos and JunB [258]

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This is particularly relevant for injectable formulations obtained outside standard pharmaceutical channels, where risks of contamination, endotoxin exposure, or improper compounding may exceed any theoretical biologic effect

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Su, J., Satchell, S

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Bhasins Insight: In my clinical experience at Care Well Medical Centre, Delhi, most cases of early greying are linked to stress, vitamin deficiencies, and modern lifestyle habits not just ageing

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