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During ER stress, stimulator of interferon genes (STING), a transmembrane protein predominantly located in the ER, responds to stress signals and promotes inflammasome activation, such as NLRP3, via the STING/ TANK-binding kinase 1 (TBK1) pathway, leading to tissue inflammation (61)

Editor information Editors and Affiliations Rights and permissions Copyright information 2025 The Author(s), under exclusive license to Springer Nature Switzerland AG About this chapter Cite this chapter Zaro, J.L., Wang, J., Shen, WC

A deficiency in iron, vitamin B12 or B6, or folate, or the bodys inability to assimilate or use a certain nutrient, can contribute to anemia

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Decreased expression of GPX4 and GSH, increased production of MDA, and characteristic mitochondrial morphological changes of ferroptosis are exhibited in the ALI mice [130]

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