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Notably, clock resetting can proceed without tim-cry dissociation, as the UPS targets the complex for degradation (Lin et al., 2023)

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The study reveals that echinatin reduced ECM stiffness surrounding cultured VSMCs and upregulated glutamate cysteine ligases (GCLs) expression, including the catalytic (GCLC) and regulatory (GCLM) subunits

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