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doi: 10.1097/QAI.0000000000001320 38

S 209 A vs S 213 A-S 217 A-S 221 A, P = 0.95

Various drugs undergo the process of oxidation

This fingerprint should link molecular signatures (e.g., co-expression of ACSL4 and 4-HNE) to histological lesions (e.g., tubular necrosis and fibrosis), enabling precise localization and quantification of ferroptosis in the renal microenvironment

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For example, one animal model out of Japan showed that administering antioxidants to mice helped preserve the function of beta cells in the pancreas, which are responsible for the production of insulin