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Global GST activity was measured as well as the activity of GPX (GSH-dependent enzymes that detoxify hydrogen peroxide) in choroid plexuses isolated from Nrf2 +/+ and Nrf2 / animals

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50 Studies of esketamine, approved by the FDA for treatment of refractory depression at doses ranging from 0.25 to 0.5 mg/kg, suggest use of single or repeated doses is unlikely to cause urothelial toxicity