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Biochemistry, ceruloplasmin

In combination, the NL-GHK-Cu complex, thanks to the attached metal ion, activates copper- and zinc-dependent superoxide dismutase (SOD), promoting endogenous antioxidant activity

This triggers the MAPK cascade, such that Ras-GTP activates Raf [also called MAPK kinase kinase (MAPKKK)], which in turn activates MEK1/2 [MAPK kinase (MAPKK)]

More prolonged gastric emptying delay: The combined effect slows down the digestion process in the stomach and prolongs the physical feeling of fullness

EW significantly mitigated neuronal damage, with immunofluorescence staining revealing an uneven MAP2 fluorescence distribution in the ICH group, indicating pronounced lesion morphology