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Although current clinical approaches, such as debride- ment, skin grafting, and advanced wound dressings, aim to improve local conditions, they largely provide symptomatic relief rather than addressing the underlying molecular and cellular dysfunction

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10.1111/hdi.12177 [DOI] [PubMed] [Google Scholar] 44

Consequently, slow product release is rate limiting in vitro 7 and in agreement with the observation that the NMT interactome is highly enriched in its own substrates 7,46

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GeMes, clusters of DNA methylation under genetic control, can inform genetic and epigenetic analysis of disease